Numerous cases of sentinel events in healthcare settings have been attributed to medical errors, such as wrong-site surgeries, postoperative complications, and medication administration mistakes. Root cause analysis (RCA) is a valuable tool used to identify the root causes and factors contributing to these incidents. RCA can be applied in healthcare settings to effectively improve patient safety by identifying causal factors and proposing an action plan to mitigate risks. In particular, medication administration errors are a significant concern, according to a systematic review published in 2020, study showed that Adverse Drug Reactions (ADRs) accounted for approximately 3.5% of hospital admission and cause of ~ 197,000 mortalities every year (Khalil & Huang, 2020). Mortality rates related to medication errors have been reported in several hospitals and clinics in the USA. This paper will examine RCA of adverse events related to medication administration errors and discuss evidence-based practices to improve patient safety.The document will also include a thorough plan for safety improvement that makes use of organisational assets already in place to solve patient safety issues. To achieve this, healthcare professionals, including nurses, must work collaboratively with the relevant stakeholders to develop and implement effective safety strategies. Root Cause Analysis of Errors in Medication Administration Medication errors can arise from various sources, such as patients, medical personnel, and nurses. These errors can result from several medication-related risks, whichinclude the number of medications taken by patients, older patient age, incorrect prescriptions, the presence of multiple comorbidities, excessive use of medications, the administration of anticoagulants, and drug interactions, as revealed by several studies (Di Simone et al., 2019).
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