NURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay Pharmacokinetics and Pharmacodynamic Principles

 

I am working and hoping to be a Nurse practitioner soon. A nurse practitioner (NP), otherwise called an Advanced Registered Nurse Practitioner (ARNP), performs tasks comparable to those of a doctor from endorsing prescription and performing minor medical procedures to requesting tests and deciphering the outcomes. NURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay.

As indicated by Arcangelo et al., (2017), pharmacokinetics refers to the development and movement of drug all through the body, including the administration, absorption, dispersion, and elimination, whereas pharmacodynamics alludes to how the medication influences the body, including therapeutic or harmful impacts. The NP must understand how medications work and intention for the use and result (Laureate Education, Inc. (Executive Producer), 2012) NURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay.

 

As practitioner students, we must educate ourselves on the elements of appropriate, safe, and complete prescription writing in all patient cases. We hypothesized that the incorporation of a pharmacist in nurse practitioner student learning could improve preparedness to prescribe as well as encourage collaboration with pharmacists as part of an interprofessional health care team. (Sabatino et al.,2017)

In a specific case during one of my shifts in the emergency room, a 42-year-old Caucasian male arrived by EMS with complaints of severe mid-sternal chest pain radiating to his left shoulder Upon evaluation. NURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay. We horridly insert two large-bore peripheral IVs and immediately completed an EKG and my colleague received an order from the Physician who was standing across from the trauma room #1. She administered Morphine 4mg and Zofran 4 mg IV to help relief what appears to be severe mid-sternal pain expressed by facial and bodily movements and asking that we relieve his pain. As I continue to obtain a proper health history when suddenly the patient had what appears to be a sudden severe adverse reaction. Patient was given Narcan 0.4 mg IV. He became unresponsive coded and was revived after ten minutes of CPR and ACLS protocol, the patient’s mental and hemodynamic status had improved and the patient was sent to the cardiac catheter lab where it was discovered that he had 35 % ejection fracture and was diagnosed with myocardial infarction. He received post-cardiac treatment and left the hospital five days laterNURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay.

The factors

The patient was given Morphine for pain in an appropriate amount but it appears that it affected the heart rather than caused an allergic reaction. Morphine is a highly effective pain killer and some health professionals use it to help alleviate serious chest pains during angina or heart attacks. Although it helps in dilating the blood vessels around the heart, it can also cause low blood pressure which can further worsen the damage caused during a heart attack. In some instances of heart attack, morphine may only mask the pain, allowing further damage to occur without the patient receiving important pain signals to the brain. (McCance et al.,2019)

Huge pharmacokinetic and pharmacodynamic changes that happen within the myocardial tissues, age, and cardiac disease may demonstrate the danger of unfavorable impacts of narcotics (Prostran et al., 2016). In this specific case, the patient had no known history of cardiac disease, or allergic to medication but after the cardiac catheterization, it noted that his heart was functioning with 35 % ejection fracture. he hearts contracts and relaxes. When your heart contracts, it ejects blood from the two pumping chambers (ventricles). When the heart relaxes, the ventricles refill with blood. No matter how forceful the contraction, the heart can never pump all blood out of a ventricle. The term “ejection fraction” refers to the percentage of blood that’s pumped out of a filled ventricle with each heartbeat because of blockage of the coronary arteries and cardiovascular disease the heart was not able to pump effectively. ( McCance et al.,2019) NURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay.

Patient was not able to give a history of cardiovascular disease and denies any history of allergies, no medical history was obtained before receiving Morphine and may have affected an injured myocardium. The nurse practitioner must make every effort to get a medical history and any pertinent information before administering medication. I believe that without the morphine the patient would have coded and presented with a different result NURS 6521 Week 1 Discussion: Pharmacokinetics and Pharmacodynamics essay.

 

References

Arcangelo, V. P.

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