Explain the concept of azotemia (including prerenal, renal, and postrenal), causes, and diagnostic measures used to identify each. 2. Identify and discuss the pathophysiology underlying one pediatric urological disorder.

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Topic 12 DQ 1
Question One.
Azotemia is a condition that occurs when there is erroneous raise of nitrogenous products and creatinine in the blood. Usually, the raise is caused by the inability of the renal system to filter waste products properly. It is usually the underlying factor in both acute and chronic kidney injury (Tyagi & Aeddula, 2021)
Prerenal azotemia – It is decreased or lack of blood flow to the kidneys due to injuries such as dehydration, over-diuresis, or intravascular depletion. It is diagnosed by a BUN test of greater than 21 mg/dl and fractional excretion of urea less than 35%.
Renal – this is the damage in the structure of the kidney especially the renal tubules, glomeruli, renal vasculature, and the interstitium. It is diagnosed by Urea Osmo less than m0sm/kg.
Post-renal – It results from complications in the ureters and bladder. The patient is diagnosed with obstruction usually with recurrent conditions of UTIs, hydronephrosis, or benign prostatic hyperplasia.

 

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