What exactly is the NCLEX? The National Council Licensure Examination (NCLEX) refers to the two standardized examinations that all candidates must pass in order to become either a Licensed Practical Nurse (LPN) or a Registered Nurse (RN). Individuals with an accredited nursing degree must pass either the NCLEX-RN or NCLEX-PN to become formally licensed. This is an important milestone in every nurse's career since it allows states to independently verify knowledge and assess a nurse's competence to perform safely. Who Takes the NCLEX Exam? Anyone who wants to work as an RN or LPN or extend their study to become an Advanced Practice Nurse (APRN) must pass the NCLEX exam. Individuals with a Practical Nursing diploma who want to become a Licensed Practical Nurse must pass the NCLEX-PN. Those with an Associate Degree in Nursing and/or a Bachelor of Science in Nursing (BSN) who want to become Registered Nurses (RNs) must pass the NCLEX-RN.