Schistosomiasis (snail fever, bilharzias) is caused by Shistosoma trematode parasites and takes two forms: urogenital and intestinal. The snail larvae infect the human host during the contact with contaminated water sources. The symptoms of intestinal schistosomiasis include abdominal pain, blood in the stool and diarrhea. Urinal form is characterized by haematuria accompanied by frequency and dysuria. According to the World health Organization, in 2014 over 61.5 million people required schistosomiasis treatment. In the African Region alone, there were over 52 million reported schistosomiasis cases (WHO, 2016). In total, it is believed that schistosomiasis accounts for around 40% of all tropical disease cases throughout the world. Therefore, this paper will investigate the impact of human schistosomiasis in some regions of sub-Saharan Africa. In addition, this paper will also assess the knowledge, attitudes and practices related to schistosomiasis in some regions of sub-Saharan Africa. Annotated Bibliography Chimberengwa, P. )., Gombe, N. )., Bangure, D. )., Tshimanga, M. )., Takundwa, L. )., & Masuka, N. ). (2014). Schistosomiasis outbreak investigation, Empandeni Ward, Mangwe District, Matabeleland South Province, June 2012; A case control study. BMC Research Notes, 7(1), doi:10.1186/1756-0500-7-623 This is a primary research study where the authors examined the factors, the etiology and the risks associated with a schistosomiasis outbreak at one elementary school in Zimbabwe.