Step 4: Integrating the Research Evidence into Decision Making This step involves applying the acquired evidence in clinical settings in order to improve the quality of patient care, patient outcomes, patient care consistency, and cost containment. It provides answers to respective PICO question for nursing. Per se, the application of this evidence is usually a complex process that involves individual clinician, clinical teams, clinical systems, and clinical organizations. Obviously, the application process should follow certain procedures as outlined by different models. Some of the key application models include: 1. John Hopkins Model 2. Stetler Model 3. Iowa Model Note that the John Hopkins Model is the most commonly used model. Step 5: Evaluating the Effectiveness of the Evidence This step entails monitoring and evaluating changes in clinical outcomes resulting from the application of the evidence. It is important in ensuring that positive outcomes are supported and negative outcomes are remedied. Evaluation can also be used to detect flaws in clinical implementation process and accurately determine the category of patients that stands the most benefits. Step 6: Dissemination of Results This step involves sharing the EBP experiences with colleagues, other clinical field professionals, and respective organizations. You are required to share answers to the entailed PICO question for nursing. Dissemination is essential for improvement of clinical practice as well as avoiding duplication of efforts. Clearly, some of the common dissemination channels include EBP rounds, conferences, professional newsletters, peer-reviewed journals, and general audience publications.