Let us investigate a comparison of various evidence-based practice (EBP) models in nursing. Various models help nurses apply evidence in a systematic and structured way to inform and enhance patient care. The Iowa Model, the ACE Star Model of Knowledge Transformation, and the Johns Hopkins Nursing Evidence-Based Practice Model will be compared here. Iowa Model: Emphasis: Primarily used in nursing practice to identify and resolve clinical concerns. Steps: Identifying the issue. Choosing an EBP committee. Evidence is being examined. Putting evidence into action. Result evaluation. Strengths: Simple stages make it simple to follow. Committees are used to emphasize teamwork. Challenges: Iterative aspect of EBP may be overlooked if regarded as linear. ACE Star Model of Knowledge Transformation: Focus: Individual, organizational, and system-level knowledge change is prioritized. Steps: Inquiry (asking questions). Evidence synopsis. Practice translation. Implementation in practice. Evaluation. Strengths: Recognizes the fluidity of knowledge transformation. Change at the organizational and system levels is emphasized. Challenges: It may be difficult for people who are new to EBP. Model of Evidence-Based Nursing Practice at Johns Hopkins: Focus: Designed to help nurses integrate research knowledge, clinical competence, and patient values in a methodical way. Steps: Develop an inquisitive mindset. Pose a clinical query. Look for the evidence. Examine the evidence critically. Compile the evidence. Examine the choice or change in practice. Strengths: Encourages curiosity by including an inquisitive spirit. Emphasis is placed on patient values. Challenges: A solid foundation in research and critical thinking may be required. Common Themes: Inquiry Spirit: All three models emphasize the significance of instilling a spirit of inquiry among healthcare practitioners. Evidence Integration: Each model places a premium on the incorporation of evidence into clinical decision-making. Patient-Centered Care (PCC): All three models place a premium on patient values and preferences. Organizational Assistance: The ACE Star Model and the Johns Hopkins Model both emphasize the significance of organizational support and change. Conclusion: While the precise processes and emphases of these models vary, they all share the fundamental concepts of incorporating research, clinical competence, and patient values into nursing practice. The model chosen may be determined by the context, the nursing team's level of experience, and the specific goals of the EBP program. Finally, successful EBP implementation necessitates a commitment to continual learning, teamwork, and the provision of high-quality, patient-centered care.