Introduction: Nursing informatics, with its emphasis on using technology to improve patient care, has yielded various benefits. However, the ethical issues surrounding the use of patient data in this context are critical. This paper digs into the ethical implications of using patient data in nursing informatics, addressing problems such as privacy, security, permission, and responsible management of sensitive information. Body: Patient confidentiality and privacy: Patient data gathering and storage in nursing informatics systems raises privacy problems. Maintaining patient trust requires ensuring the confidentiality of sensitive information. To protect patient data from unwanted access, ethical nursing informatics practices include installing strong security measures, encryption techniques, and access controls. Autonomy and Informed Consent: The ethical principle of autonomy stresses individuals' right to make informed decisions about how to use their health information. Patients' informed consent for the collection, storage, and use of their data should be prioritized by nursing informatics. Transparent communication about how the data will be utilized enhances trust between healthcare providers and patients. Accuracy and Integrity of Data: The accuracy and integrity of patient data are also ethical considerations. Incorrect or insufficient information might lead to poor healthcare decisions and jeopardize patient safety. Nursing informatics professionals must adhere to ethical standards in data entry, validation processes, and routine checks to ensure the accuracy and reliability of the information stored in electronic health records. Data Ownership and Control: Addressing the ethical implications of data ownership involves clarifying who has control over patient information and how it can be utilized. Policies should clearly define patients' rights to access, amend, or restrict the use of their data. Ethical nursing informatics practices involve empowering patients to have greater control over their health information. Data Sharing and Interoperability: Interoperability, while crucial for seamless healthcare delivery, raises ethical concerns related to data sharing between different healthcare entities. Nursing informatics professionals must consider the ethical implications of data sharing, ensuring that patient consent is obtained and that information exchange adheres to established privacy and security standards. Mitigating Bias in Data Algorithms: The use of algorithms in nursing informatics for decision support can inadvertently introduce biases, leading to disparate outcomes for certain patient populations. Ethical considerations include regularly auditing algorithms for bias, transparency in algorithmic decision-making, and ongoing efforts to minimize bias and ensure fair and equitable treatment of all patients. Conclusion: As nursing informatics continues to evolve, it is imperative to navigate the ethical complexities surrounding patient data conscientiously. Prioritizing patient privacy, informed consent, data accuracy, ownership, and mitigating biases in algorithms are essential components of ethical nursing informatics practice. By upholding these ethical principles, healthcare professionals can harness the power of technology to enhance patient care while preserving the dignity, autonomy, and trust of the individuals they serve.