Nursing plays a key role in resolving healthcare disparities in global health, particularly in low- and middle-income countries (LMICs). This paper investigates the challenges and opportunities for nurses to contribute to global health and overcome discrepancies in healthcare delivery. Understanding Healthcare Disparities in Low-Income Countries: Disparities in healthcare access and outcomes in LMICs are frequently founded in socioeconomic issues such as poverty, a lack of education, and limited access to essential healthcare services. Inadequate healthcare infrastructure and limited resources lead to inequities, limiting the ability to deliver basic health services, respond to epidemics, and fulfill the different healthcare demands of communities. Nurses' Role in Global Health: Nurses are well-positioned to provide primary care and preventative services, addressing the underlying causes of health disparities. Their responsibilities include health promotion, disease prevention, and community education in order to promote population health. Capacity Building: Nurses help to build capacity by training and teaching healthcare personnel in low-income countries. Sharing expertise in nursing practice, leadership, and public health is one way to boost local healthcare systems. Obstacles to Addressing Healthcare Disparities: Nurses working in LMICs sometimes encounter limits due to a lack of resources, such as healthcare personnel, medical supplies, and money. Overcoming these difficulties will necessitate creative solutions and partnership with local communities. Cultural Competence: Understanding and appreciating multiple cultural contexts is essential for effective global health nursing practice. Nurses must be culturally competent in order to create trust and provide care that is consistent with the values and beliefs of the communities they serve. Disparities Reduction Strategies: Community Engagement: Active community engagement is required for successful global health projects. Nurses can collaborate with local communities to identify specific health needs, provide information, and devise long-term interventions that address the underlying causes of inequities. Partnerships and Collaboration: International organizations, local governments, and non-governmental groups must work together. Nurses can help to develop effective partnerships that pool resources, share expertise, and undertake coordinated efforts to enhance healthcare in low- and middle-income countries. Policy Change Advocacy: Nurses can campaign for policy changes at both the local and global levels to address systemic factors that contribute to healthcare inequities. This includes pushing for additional money, improved infrastructure, and policies that emphasize disadvantaged communities' health needs. Initiatives in Education and Training: Training Local Healthcare Workers: Nurse education and training efforts can help local healthcare workers improve their skills. This includes creating educational programs, holding workshops, and establishing mentorship activities to strengthen the local workforce. Nursing can support sustainable healthcare practices in LMICs by promoting community-based and culturally responsive care approaches. This includes combining traditional healing techniques as well as allowing communities to take charge of their own health. Global Health Emerging Technologies: Telehealth and Mobile Health Applications: Technology, such as telehealth and mobile health applications, has the potential to break down geographical barriers and increase access to healthcare services in rural areas. These technologies can be used by nurses to deliver virtual consultations, health education, and remote monitoring. Data Analytics for Public Health: By identifying trends, predicting disease outbreaks, and tracking healthcare outcomes, data analytics can help inform public health measures. Nurses can help gather and analyze data, allowing for evidence-based decision-making in global health. Ethical Issues in Global Health Nursing: Ethical nursing practice in global health necessitates cultural sensitivity and respect for local traditions and beliefs. To ensure that their care is both effective and respectful, nurses should seek to learn and incorporate cultural nuances. Ethical decision-making include lobbying for equitable resource allocation and ensuring that solutions focus the most vulnerable groups. Nurses can be critical participants in ethical conversations concerning resource distribution and allocation. To summarize, nursing in the context of global health in LMICs is a complicated activity that necessitates a comprehensive strategy to addressing healthcare inequities. Nurses may make a substantial contribution to closing the global healthcare access and outcomes gap by embracing community participation, lobbying for legislative reforms, harnessing emerging technologies, and adhering to ethical values. Nurses may play a transformative role in achieving global health equity through teamwork, cultural competence, and a dedication to sustainable practices.